Custom Peptides
Cayman Chemical 1MyrIstoyl3Butyrylracgly 10mg
A diacylglycerol containing myristic acid at the sn-1 position and butyric acid at the sn-3 position
Cayman Chemical GlobotrIaosylcRamIDporcIn 10mg
A sphingolipid; found in mammalian cell membranes; act as receptors for Shiga and Shiga-like toxins in vitro and in vivo; accumulate in various cells in patients with Fabry disease; interacts with HIV gp120 to prevent its interaction with chemokine co-receptors and subsequent fusion of HIV to host cell membranes
Cayman Chemical VU590hydrochlorIde 10mg
A small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also causes 70% inhibition of KCNJ13 at 10 µM; has no effect on the related channels KCNJ2 (Kir2.1) and KCNJ10 (Kir4.1) at a concentration of 10 µM
Cayman Chemical 1ArachIdoyl2PalmItoyl3Ol 10mg
A triacylglycerol; has been found in butterfat; levels are increased in Plin5-overexpressing mice fed a high-fat diet
Cayman Chemical 7Benzyloxy4 trIfluoromthy 10mg
A fluorogenic substrate for CYP1A2 and CYP3A; HFC is released upon enzymatic cleavage by CYP1A2 and CYP3A and its fluorescence can be used to quantify CYP activity; ex/em = 410/510 nm, respectively
Cayman Chemical TrIazavIrIn 10mg
An antiviral agent; inhibits lung viral accumulation in a mouse model of H5N1 influenza A infection at 1 mg/kg; inhibits platelet aggregation in a rat model of LPS-induced hypercytokinemia at 20 mg/kg
Cayman Chemical pmthylNsalcyloyl Tryptam 10mg
A neuroprotective agent; reduces LPS-induced NO production in C6 cells and BV-2 microglia (IC50s = 7.48 and 4.94 µM, respectively); reduces LPS-induced production of TNF-α and PGE2 and increases production of IL-10 in BV-2 microglia at 40 µM; decreases cortical and hippocampal Aβ plaque formation and neuronal pyroptosis, as well as improves spatial learning and memory in a mouse model of Aβ-induced Alzheimer’s disease from 25-100 mg/kg
Cayman Chemical Tocopherol 10mg
A form of vitamin E with antioxidant and anti-inflammatory properties; traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays; reduces PGE2 synthesis induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells (IC50s = 7.5 and 4 μM, respectively); inhibits LPS-induced nitrite release and iNOS expression in RAW 264.7 cells at 10 μM and reduces COX-2 activity in A549 cells pretreated with IL-1β; serum levels are decreased in patients with cardiovascular disease
Cayman Chemical HypaconItIn 10mg
A diterpene alkaloid with diverse biological activities; inhibits nerve stimulation-evoked contractions in isolated mouse phrenic nerve-diaphragm muscle preparations (IC50 = 118 nM); prevents carrageenan-induced paw edema in mice at 0.025 mg/kg; reduces acetic acid-induced writhing in mice (ED50 = 0.1 mg/kg); toxic to mice (LD50 = 1.9 mg/kg, s.c.)
Cayman Chemical 5Fluoropentyl3pyrIdInoyln 10mg
A synthetic CB which shares the aminopentylindole structure of potent CBs like JWH 018
Cayman Chemical Ginsenoside Ro 10MG
A non-steroid glycoside with diverse biological activities; inhibits LPS-induced ROS and NO release as well as iNOS and COX-2 protein expression in RAW 264.7 mouse macrophages at 200 μM; dose-dependently inhibits thrombin-induced human platelet aggregation in vitro and thrombin-induced DIC in rats at 100 mg/kg; increases the 20-day survival of Sendai virus-infected mice at 1 mg per day for three days prior to infection; stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth at 0.2 mg per animal topically
Cayman Chemical ProstaglndIn B2 10mg
PGB2 is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 UG/kg).{1301}
Cayman Chemical PhenformInd5hydrochLRIde 10mg
An internal standard for the quantification of phenformin by GC- or LC-MS